Reagent Products
for Preclinical Development
XenoFluor™ Fluorescence Labeling Kits
XenoFluor labeling kits provide a flexible solution for labeling proteins, peptides or antibodies. Available in a 680 nm or 750 nm dye formulation, XenoFluor kits are ideal for in vivo optical imaging.
The XenoFluor 680 nm and 750 nm 2.0 mg labeling kits contain three vials of Near InfraRed (NIR) emitting dyes that can label proteins, peptides or antibodies. Each vial is optimized for labeling and purifying 2 mg of antibody per conjugation reaction; comparable amounts of other proteins (>30 kDa) can also be labeled. This kit is ideal for tumor targeting in small animals using the IVIS® Imaging Systems.
Download XenoFluor Product Sheet
Light Producing Cells and Microorganisms
Xenogen light producing lines currently include cancer cells, bacteria, and fungi tagged with luciferase gene constructs (firefly or bacterial). Xenogen supplies cell lines and microorganisms that incorporate bioluminescent reporters designed to allow non-invasive, real-time in vivo assessment of the spread and growth of cancers and specific infectious diseases. These tagged organisms and cells allow researchers to develop models that provide new insight into the mechanisms of action and overall efficacy of drug candidates. Xenogen light producing oncology models are both primary and metastatic, and include breast and prostate cancer, melanoma, and other lines currently in development. Xenogen light producing infectious disease models include Gram-positive and Gram-negative bacteria, and fungi.
Light Producing Animal Models
Xenogen light producing animal models are engineered genetically modified to emit light when a specific gene is active. They are intended for use as a research tool for in vivo validation of drug candidates or drug targets, and to assess the ADME and safety/toxicity of potential drugs or other chemicals. Xenogen light producing animal models expand the potential applications for real-time in vivo imaging to include virtually every therapeutic area of interest in the life sciences.
View full list of current light producing animal models
