Xenogen Biosciences, a subsidiary of Xenogen Corporation, has a long and respected track record in the design and production of genetic modifications in animal models using pronuclear microinjection and/or gene knockout/knockin techniques, and breeding services. To date, Xenogen has produced over 8,000 unique transgenic mice and rats from over 2,500 transgene constructs. More than 97% of all gene constructs have successfully produced transgenic mice and rats, or gene knockout lines. In sum, Xenogen offers the biomedical community a long-proven and integrated array of genetically-modified animal creation capabilities, as well as a comprehensive phenotyping platform to characterize such animal lines, and an in vivo compound profiling program to characterize the effects of compounds in rodent models.
Xenogen's IVIS Iimaging Systems, which provide innovative imaging technologies, including in vivo biophotonic imaging, can also play an important role in furthering genetic modification projects or those involving custom light producing animal models.